Nasol Advance nasal spray 15ml

Nasol Advance nasal spray 15ml

Oxymetazoline hydrochloride - a drug derived imidazoline having expressed Adrenomimeticalkie activity. When applied topically, oxymetazoline hydrochloride has a stimulating effect on alpha-adrenergic vascular smooth muscle layer of the nasal mucosa. Because stimulation of alpha-adrenergic vasoconstriction noted, reduction in vascular permeability. In addition, when using the drug there is a decrease swelling and redness of the mucous membranes of the nose, paranasal sinuses and Eustachian tube. Oxymetazoline hydrochloride belongs to a group of long-acting nasal decongestants. When applied topically, the drug is not absorbed into the systemic circulation and resorptive activity.

Included in the preparation camphor, menthol and eucalyptol have anti-inflammatory, antiseptic and anti-edema effect. Furthermore, these active ingredients contribute to the normalization of nasal secretion and improves expectoration of mucus. Nazol Advanced also has a moisturizing effect on the mucous membranes of the nose, prevents excessive dryness of mucous membranes, which can develop as a result of alpha-agonists. Eucalyptol inhibits the production of proinflammatory cytokines, reduces the intensity of the inflammatory process. Camphor and eucalyptol have pronounced bactericidal and fungicidal activity, furthermore, camphor and eucalyptol reduce the ability of viruses to enter and fixed on the mucosa of upper respiratory tract.
Intranasal application of oxymetazoline hydrochloride is not absorbed into the systemic circulation and resorptive activity.
Menthol, camphor and eucalyptol in a minor amount penetrating into the systemic circulation. Derived from the systemic circulation via the lungs.

Indications for use:
The drug is used for treatment of acute rhinitis, which are accompanied by respiratory viral and bacterial etiology. Including the drug is used in the treatment of patients suffering from acute respiratory diseases, flu and colds, which are accompanied by rhinitis.
Advance preparation Nazol used for the prevention and relief of swelling of the mucous membranes of the nose during surgery and diagnostic procedures in the nose. In addition, it is recommended to use the drug during rehabilitation after surgery of the nose to prevent the development of edema and hyperemia of the mucous membranes of the nose.

How to use:
The drug is used intranasally. Before applying, clean the nasal passages. After that, take a bottle of spray vertically upward and gently introduced into the nasal passage, the second nostril closed and while breathing through the nose of a squeeze bottle until it stops. Thus, produce both nasal injection stroke.
The duration of treatment and the dose determined by the attending physician for each patient depending on the nature of the disease and individual patient characteristics.

Adults and adolescents over the age of 12 years are usually prescribed for 2 doses of the drug in each nostril 2 times a day. Between uses of the drug are advised to observe an interval of at least 12 hours. The duration of treatment is not more than 3 days, if the treating physician does not otherwise directed.
Children aged 6 to 12 years are usually given 1 dose of the drug in each nostril 2 times a day. Between uses of the drug are advised to observe an interval of at least 12 hours. The duration of treatment is not more than 3 days, if the treating physician does not otherwise directed.
It is recommended to use an individual bottle for each patient to prevent the spread of infection.
If after 3 days after the start of the drug in the patient Nazol Advanced saved redness and swelling of the mucous membranes of the nose should contact your doctor for further diagnosis.

Side effects:
The drug is generally well tolerated by patients, and in rare cases noted the development of a burning sensation and tingling in the nose. With the frequent use of the drug, as well as when using the drug for more than 3 consecutive days may develop side effects such as nausea, headache, fatigue and impaired sleep and wakefulness. With long-term use of the drug is marked decrease its effectiveness.

Contraindications:
Hypersensitivity to the drug.
The drug is not used for the treatment of patients with atrophic rhinitis.
Renal failure.
The drug is not prescribed for patients with advanced prostatic hypertrophy, hyperthyroidism, and patients with narrow angle glaucoma.
The drug is contraindicated in patients suffering from diseases of the cardiovascular system, in particular drug is not indicated for severe forms of hypertension, atherosclerosis and tachysystole.
The drug is not used for the treatment of children under the age of 6 years. Caution should be exercised when using the drug to treat children aged from 6 to 12 years.
The drug is prescribed with caution to women during pregnancy and lactation.

Pregnancy:
The drug can be assigned during pregnancy and breastfeeding health care provider if the expected benefit to the mother is higher than the potential risk to the fetus or child.

Interactions with other drugs:
Preparation is not used in conjunction with other drugs that cause vasoconstriction, regardless of the route of administration of these drugs.
The drug is not recommended for use in conjunction with preparations of monoamine oxidase inhibitors.

Overdose
When used according to instructions overdose is impossible.
In the application of excessive doses of the drug over an extended period may develop systemic side effects characteristic of oxymetazoline, including high blood pressure and abnormal heart rhythm.
If overdose should stop using the product and contact your doctor.

Product:
Nasal spray for 15 or 30 ml in plastic bottles with spray, 1 plastic bottle in a cardboard box.

Storage:
The drug should be stored in a dry place away from direct sunlight at temperatures between 15 and 30 degrees Celsius.
Shelf life - 2 years.

Synonyms:
Noksprey

Ingredients:
1 ml nasal spray contains:
Oxymetazoline hydrochloride - 0.5 mg;
Excipients, including menthol, eucalyptol and camphor.

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