For treatment: arthritis, osteochondrosis
60 capsules 500 mg
Mode of action:
Structum - chondroprotective agent for oral administration. Structum active component comprises sodium chondroitin sulfate . Chondroitin - a substance that is the structural basis of cartilage and bone . Acceptance of endogenous chondroitin helps to restore and maintain the normal structure of the cartilage matrix by increasing the anabolic activity of chondrocytes and stimulate the synthesis of proteoglycans. In addition, drug Structum chondroprotective action is realized by inhibiting the activity of interleukin -1 beta, adversely affecting the cartilage matrix, and enzymes elastase and collagenase which lead to excessive cartilage matrix degeneration .
Structum also stimulates the synthesis of hyaluronic acid and normalizes the viscosity of synovial fluid, which contributes to the normalization of homeostasis synovial joint environment .
Chondroitin has some antioxidant and enzymatic action, which leads to suppression of inflammatory reactions.
When taken orally, the drug Structum active ingredient is rapidly absorbed in the digestive tract and reaches peak plasma concentrations for 4 hours. Some of chondroitin accumulates in synovial fluid.
Excreted mainly chondroitin intestine.
Indications for use :
Structum used in the treatment of patients suffering from degenerative- dystrophic diseases of the spine and joints, including the drug is prescribed for osteoarthritis and intervertebral osteochondrosis .
How to use:
Structum intended for oral administration. The capsules are encouraged to take full ( in case of damage the integrity of the capsule can change the pharmacokinetic profile and reduce the effectiveness of the drug). The drug Structum take with or without food, it is recommended to wash down the capsule with sufficient drinking water. Duration of therapy and dose of chondroitin sulfate solution determined by the physician .
When degenerative diseases of the spine and joints, usually prescribe medication intake of 1 capsule twice a day Structum .
Recommended daily therapeutic dose of 1000 mg of sodium chondroitin sulfate .
For maintenance therapy dose is determined individually.
The duration of the course of therapy with Structum is 3 to 6 months. If necessary, after 2-5 months, appoint a second course of receiving chondroitin .
The drug Structum generally well tolerated by patients. During the study, in some cases, noted the development of undesirable effects from the digestive tract, including nausea and vomiting, and dyspepsia .
In patients with hypersensitivity to chondroitin Structum while taking the drug may develop erythema, allergic dermatitis, urticaria, maculopapular rash, and angioedema .
The development of side effects is recommended Structum stop taking the drug and seek medical advice .
Structum should not be administered to patients with a history of hypersensitivity reaction to chondroitin sulfate sodium salt or other ingredients .
In pediatric practice, the use of the drug Structum only allowed to treat children older than 15 years.
Not recommend use of the drug Structum women during pregnancy, since the effect of chondroitin sulfate sodium salt for the development of the fetus and the pregnancy is not known.
Use of the drug Structum during breast -feeding is not recommended. Should avoid taking chondroitin sulfate sodium salt during lactation can not, should decide on the termination of breastfeeding.
Interactions with other drugs:
Chondroitin sulfate sodium salt in the combined use may potentiate the effect of antiplatelet funds, fibrinolytic agents and anticoagulants.
When you receive excessive doses Structum patients may increase the severity of adverse effects. Before the drug in doses much higher than recommended, hospitalization is shown and monitoring of the patient. If necessary, symptomatic treatment.
Structum capsule of 12 pieces in blister packs of aluminum foil and plastic materials, cardboard unit invested 5 blister packs .
Structum capsules should be stored and transported in its original packaging at a temperature range of 15 to 25 degrees Celsius.
Subject to the recommendations of the storage preparation Structum pass for 3 years after graduation.
Chondroitin Arthritis, Artron Hondreks.
1 capsule contains drug Structum :
Chondroitin sulfate sodium salt - 500 mg ;
Additional ingredients .