The drug improves blood flow to the brain, particularly in areas of ischemia, hypoxia enhances the portability of brain cells, dilates blood vessels of the brain, mainly by reducing the resistance, without affecting the system parameters (BP, PR, HR).
Vinpocetine inhibits phosphodiesterase, which leads to the accumulation of cAMP. Increased concentration of cAMP in the vessel wall, leading to its dilatation, a decrease in platelet aggregation. Vinpocetine enhances the metabolism of biologically active substances: noradrenaline and serotonin, which improves blood rheology, deformation contributes to red blood cells.
Improves delivery of oxygen to the cells, increases the adaptation to hypoxia. Increases the absorption of glucose and its utilization.
- Transient ischemic attack;
- Stroke and postapoplectic period;
- Traumatic brain injury;
- Encephalopathy of different genesis;
- Atherosclerosis of cerebral vessels;
How to use:
The drug is intended for intravenous drip.
The initial dose is 20mg (4ml) of the drug dissolved in 0.5-1 liters of normal saline or 5% glucose solution. Slowly (every 3-4 days) increase the dose to the maximum, which is 1 mg per kg body weight per day. The course of therapy with 10 - 14 days after the dose is gradually reduced, then move on to maintenance therapy, in pill form. Appoint 5 - 10 mg (1 - 2 tablets) 3 times a day for a long time.
Side effects are rare, may develop: dizziness, nausea, redness of skin, hot flashes, disturbances of the heart (increased frequency of heart rate, arrythmia, deterioration of intraventricular conduction), thrombophlebitis at the site of injection.
Intolerance to any component of the drug.
Pregnancy and lactation.
Severe cardiac arrhythmias.
Acute stage of hemorrhagic stroke.
Coronary heart disease, severe course.
Pregnancy - contraindication to the drug.
Interaction with other drugs:
Do not administer heparin - increases the risk of bleeding.
Store in a place, hidden from sunlight at a temperature not exceeding 25 degrees Celsius.
Vinpocetine - 5 mg per 1 ml
Dopoplnitelnye ingredients: ascorbic acid, sodium metabisulfite, tartaric acid, benzyl alcohol, sorbitol, water for injection.
Vinpocetine - 5 mg
Additional ingredients: magnesium stearate, talc, corn starch, lactose, silicon dioxide.
With care the patient having a lengthening of the interval Q-T. In hemorrhagic stroke, a drug can not be started earlier than in 5 - 7 days.
When appointing a drug elderly patients must take into account that the drug often causes side effects in this group of patients.
Before using the drug Vinpocetine you should consult your doctor. This instruction is given a free transfer and is intended solely for information. For more information, please contact the manufacturer annotations.