Enzystal contributes to quick and full digestion of food, eliminates the symptoms of intestinal problems, contributes to secretion of the pancreas, stomach, and small intestines enzymes and bile from the gallbladder
80 tablets
The composition of the medicinal product:
- active ingredient : 1 tablet contains 192 mg of pancreatin ( lipase 6000 FIP units, amylase 4500 U FIP, FIP Protease 300 units ) hemitselyulazy 50 mg, 25 mg of bile extract ;
- inactive ingredients : lactose monohydrate, magnesium stearate, colloidal silicon dioxide, cellulose atsetylftalat, dietylftalat, sugar Pharmacy, calcium carbonate, talc, acacia, gelatin, titanium dioxide (E 171), yellow wax.
Combination drug:
Enzymes contained in the product, facilitate digestion of proteins, fats, carbohydrates and promote more complete absorption of the latter in the small intestine. Extract promotes bile emulsification of fats, increases the activity of lipase improves fat absorption and fat -soluble vitamins. Enzyme hemicellulose contributes to the breakdown of cellulose. These properties of the drug leads to improved functional status of the gastrointestinal tract, normalize digestion.
The drug is not absorbed and acts in the lumen of the intestinal tract. Content is protected by acid- coated tablets, which prevents inactivation of enzymes (which are part of the drug) hydrochloric acid of the stomach. Solvation shell and release of enzymes occurs in the small intestine, that is, alkaline environment that is optimal for the manifestation of enzyme activity.
Indications to use:
- Mild to moderate degree of violation of exocrine pancreatic function in chronic pancreatitis, except in cases of exacerbation of chronic pancreatitis and to improve digestion after resection of the stomach, flatulence and diarrhea some cases non-infectious origin.
- To improve digestion individuals with normal function of the gastrointestinal tract in case of violations of nutrition ( consumption of large quantities of food, eating fatty, fried or unusual food, irregular meals, etc.) in violation of the chewing function.
- As a tool for the effective assimilation of fat-soluble vitamins and certain drugs ( Pasco, sulfonamides, antibiotics).
Contraindications:
Hypersensitivity to the drug, the pancreatic enzymes of animal origin. Acute hepatitis, jaundice, obstructive bowel obstruction, acute pancreatitis, acute chronic pancreatitis.
Appropriate precautions for use:
- Product contains sugar, which should be considered for patients with diabetes.
- The drug contains lactose, therefore patients with rare hereditary form of galactose intolerance, lactase deficiency or glucose- galactose syndrome malabsorption should not use the drug.
- Used with caution in cystic fibrosis.
- During the recovery or expansion in the diet drug can be taken only under medical supervision.
Particular caution:
- Use during pregnancy and lactation.
- Safety of the drug during pregnancy and lactation poorly studied. Use of the drug during pregnancy and lactation is possible only if the expected benefit to the mother outweighs the potential risk to the fetus or child.
- Influence on ability to drive a car or operating machinery.
Children:
Do not apply to children.
Dosage and Administration:
Assign adults 1 tablet with some liquid during or immediately after each meal. Tablets should not be chewed. If necessary, the dose may be increased to 2 tablets.
The duration of treatment can range from a few days ( indigestion due to eating disorders ) to several months or even years (if needed constant replacement therapy ).
Overdose:
Cases of overdose have been observed. With prolonged use at high doses may develop hyperuricemia, hiperurykozuriyi. Perhaps growing manifestations of adverse reactions. Treatment is symptomatic.
Side effects:
Using the drug may cause side effects :
- From the digestive tract : nausea, diarrhea, abdominal pain, vomiting, bloating, possible intestinal colic, constipation, decreased endogenous synthesis of bile acids. Side effects from the digestive tract and may be due to the underlying disease ;
- Of the skin : skin rash, hives, itching, redness of the skin.
- Allergic reactions, watery eyes and sneezing.
- With prolonged use at high doses may develop hyperuricemia.
Possible perianal irritation, irritation of oral mucosa, especially at high doses.
In some cases, after taking high doses of pancreatin have been described cases of stricture formation in the ileocecal region and ascending colon of the large intestine in patients with cystic fibrosis.
Interaction with other medicinal products and other forms of interaction:
Enzystal promotes efficient digestion of fat-soluble vitamins, sulfonamides, antibiotics, Pasco. It reduces iron absorption with prolonged use. Concomitant use of antacids that contain calcium carbonate and / or magnesium hydroxide may reduce the effectiveness Enzystalu. Cimetidine increases the effect of the drug.
Shelf life:
3 years.
Storage:
Keep at temperature not exceeding 25 ° C, away from children, dry place.
Packing:
10 tablets in a blister, 2 or 8 blisters in carton box.
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