Exforge during pregnancy:
Exforge is contraindicated in pregnant women. The drug is not prescribed, if a woman is planning a pregnancy. Possible risk to the fetus due to the influence of the renin-angiotensin system. In establishing pregnancy drug overturned.
Exforge interaction with other drugs:
The drug, the pharmacological group of drugs results or physico-chemical interaction with the drug Exforge
Beta-adrenoceptor blockers Potentiation of antihypertensive and anti-anginal effects. Remedy associated with taking amlodipine reflex tachycardia. It is necessary to control blood pressure
Organic nitrates Summation antianginal action. Strengthening reflex tachycardia, the risk of hypotension
Inhibitors of CYP3A4 Increased plasma concentrations (PC) amlodipine
Inducers of CYP3A4 isoenzyme (phenytoin, carbamazepine, primidone, drugs St. John's wort, rifampicin, phenobarbital, fosphenytoin) Reduction of amlodipine PC
The risk of hyperkalemia potassium-containing drugs
Potassium-sparing diuretics, risk of hyperkalemia
The weakening of the hypotensive effect of NSAIDs
Diuretics The risk of deterioration of renal function, the risk of hypoglycaemia
Antidiabetic drugs hypoglycemia Gain
Blockers alpha-adrenoceptor Increased hypotensive effect
Lithium Drugs Decrease lithium excretion by the kidneys, increase the toxicity of lithium-containing medicines
Funds for general anesthesia Significant hypotension
Official reports of drug Exforge overdose has been reported. It is theoretically possible development of hypotension, dizziness, reflex tachycardia, shock. If swallowed a large number of tablets should cause vomiting, stomach hold cleaning, take drugs, sorbents. The position of the patient with an overdose and the development of hypotension - lying with raised legs. Perhaps the appointment of vasoconstrictor drug, the use of calcium gluconate. Hemodialysis is ineffective.
Exforge product form:
Exforge drug is marketed in tablet form. Filling Machine are as follows:
- Table. 5/80 mg 14 pcs .;
- Table. 5/80 mg 28 pcs .;
- Table. 5/160 mg 14 pcs .;
- Table. 5/160 mg 28 pcs .;
- Table. 10/160 mg 14 pcs .;
- Table. 10/160 mg 28 pcs.
Exforge storage conditions:
Storage temperature pill Exforge - up to 30 degrees Celsius. The product is fit for 3 years from the production date.
1 tablet contains Exforge 5/80 mg amlodipine besylate 6.94 mg, 80 mg valsartan. Auxiliary components: MCC, crospovidone, magnesium stearate, PEG 4000, silica, talc, titanium dioxide, iron oxide yellow, water, hypromellose.
1 pill Exforge 5/160 mg contains amlodipine besylate 6.94 mg, valsartan 160 mg. Auxiliary components: MCC, crospovidone, magnesium stearate, PEG 4000, silica, talc, titanium dioxide, iron oxide yellow, water, hypromellose.
1 pill Exforge 10/160 mg amlodipine besylate contains 13.87 mg, 160 mg of valsartan. Auxiliary components: MCC, crospovidone, magnesium stearate, PEG 4000, silica, talc, titanium dioxide, red iron oxide, water, hypromellose.
Exforge pharmacological group:
Cardiovascular drugs: Antagonists of calcium ions
Exforge active ingredients:
When CC 30-50 ml / min dosage of the drug Exforge correction is required.
The drug is not Eksfrzh relieves withdrawal symptoms when you stop receiving beta-blockers. Because of this, the abolition of the beta-blockers spend mild.
Before therapy requires correction fluid and sodium in the body. Initiation of therapy is carried out under the supervision of a physician.
With the development of arterial hypotension, the patient is placed in a prone position, legs lifted, carried infusion nat. solution to aid in the stabilization of blood pressure. After stabilization, therapy may be continued.
Driving of vehicles, hazardous activities while using the drug can become a life-threatening occupation because of side effects in the form of dizziness, asthenia.