Indications: an ischemic insult, traumatic damages of a brain, a delay of intellectual development in children; the frustration connected with deficiency of attention at children.
5 ampules 5 ml
Cerebrolysin pharmachologic effect:
It improves metabolism in brain tissue. Cere contains biologically active amino acids and peptides, which are the basic units of brain metabolism (metabolism). Penetrating through the blood-brain barrier (the barrier between blood and brain tissue), regulates intracellular drug metabolism and improves synaptic. transmission (the transmission of nerve excitation). As a result of its introduction increases the efficiency of aerobic energy metabolism (the body processes energy formation in the presence of oxygen), improves intracellular protein synthesis, reduced the negative impact of lactic acidosis (acidification due to an excess of lactic acid). This effect, combined with the stimulation transsynaptic transmission provides neuroprotective (protects brain cells) action of the drug, that is, increases the survival of neurons (brain cells) in hypoxia (insufficient oxygen supply to tissues, or violation of its assimilation) and other damaging influences.
Cerebrolysin, indications for use:
Diseases accompanied by disorders of the central nervous system (encephalitis / inflammation of the brain /), cerebrovascular accidents, brain surgery, retardation of mental development in children, psychiatric diseases, accompanied by distraction, weakening of memory, and others.
Cerebrolysin mode of application:
Of fundamental importance to achieve optimal effect are the use of adequate doses of the nature of the disease the drug and the correct method of administration.
In the acute stage of stroke (cerebrovascular accidents) - hemorrhagic (caused by rupture of cerebral blood vessels) and ischemic (caused by inadequate blood flow); in severe forms of meningitis (purulent inflammation of the meninges), encephalitis, directly after severe traumatic brain injury and brain surgery (depending on the degree of depression of consciousness) cerebrolysin should be administered daily by intravenous infusion for 10-30 ml in 100-200 ml of isotonic solution of sodium chloride for 60-90 minutes. This category of patients cerebrolysin appointed for 10-25 days. Turning p drug. complex therapeutic interventions in these clinical situations promotes more rapid regression (regression) disturbances of consciousness and a clear reduction (or elimination) of neurological defect, as well as normalization of the EEG characteristics (EEG - characteristics of brain electrical activity).
In the residual period of stroke (residual symptoms after acute stroke), severe neyroinfekiy (infectious diseases of the central nervous system) and Cerebrolysin brain injury assigned intravenous bolus 5-10 ml daily for 20-30 days. If necessary, treatment of similar duration can be repeated after 3-4 months. Under these pathological conditions influenced cerebrolysin faster and more fully recovers vital activity regress (decrease) changes in the EEG characteristics.
In milder cases, the drug is administered intramuscularly, 1-2 ml. The course of treatment - 20-30 injections.
Appointment cerebrolysin efficiently and with initial forms of cerebrovascular disease (caused by vascular changes in the brain), as well as dyscirculatory eniefalopatii (brain disease caused by chronic cerebral ischemia). Results of administration characterized by a decrease of asthenic syndrome (obshego decrease functional activity of the body), and an increase in performance, but the degree of effectiveness largely depends on the severity of cerebrovascular insufficiency. In these cases, the drug is administered intramuscularly for 1 to 2 ml. The course - 20-30 injections.
In psychiatry cerebrolysin successfully used in psychoorganic syndrome. Introduce 5-10 ml intravenous bolus. The course of treatment consists of 20-25 injections. His appointment is one of the most effective measures of compensation defect of mental activity in dementia of various origins' (dementia of various origin). Drip intravenous administration of 10-20 ml of the product in 100-250 ml of isotonic sodium chloride solution (treatment - 20-30 injections) can achieve a temporary regression of memory disorders and attention, improve the performance of activities of daily living. Therefore dementia shows the assignment of repeated courses of Cerebrolysin treatment. When endogenous depression (depressed as a result of mental illness) resistant to antidepressants (not amenable to treatment with antidepressants), improving the condition of patients usually occurs after 10-15 intravenous injections (5 ml). After sessions of electroconvulsive and insulin-shock therapy mental activity of patients recovering from 3-5 intravenous drip of 10-15 ml of the product in 100-250 ml of isotonic sodium chloride solution. Children with mental retardation drug is prescribed intramuscularly, 1-2 ml daily for a month. Similar courses may be repeated 2-3 times a year. In patients with moderate mental defect, its application is preferred.
Cerebrolysin side effects:
Feeling the heat, rarely - increase or decrease in body temperature.
Cerebrolysin contraindications:
Pregnancy, severe renal dysfunction, allergic diathesis. Incompatible with the amino acid solution.
Cerebrolysin product form:
In one ampoule and 5ml of a 5% solution.
Cerebrolysin storage conditions:
In dry place.
Cerebrolysin composition:
Freed from the protein hydrolyzate brain substance. It contains amino acids (85%) and low molecular weight peptides (15%). 1 ml of the solution corresponds in amino acid content of about 1 g of fresh brain tissue.
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