Nifuroxazide (Nifuroxazidum) 100mg #24

Nifuroxazide (Nifuroxazidum) 100mg #24

Mode of action:
By nifuroxazide most sensitive pathogens causing intestinal diseases: Salmonella, Staphylococcus aureus, Enterobacter, Escherichia coli, Klebsiella, Shigella, yersinii, Vibrio cholerae. Inactive it only for Pseudomonas and some strains of Proteus.
The drug may act as bacteriostatic and bactericidal effect of this dose-dependent. Nifuroxazide mechanism of action is based on inhibition of the enzyme dehydrogenase activity and abuse of protein synthesis by cells of bacteria. In moderate doses of the drug did not inhibit the growth of normal intestinal flora, does not cause the emergence of strains of bacteria resistant to antimicrobial agents. If an intestinal infection caused by viruses, warns nifuroxazide joining secondary infection.
Nifuroxazide not absorbed in the stomach, thereby creating a high concentration of active substance in the intestine. Due to the peculiarities of pharmacokinetics of the drug, it has no systemic effects (in the blood gets in small amounts), excreted in the feces.

Indications for use:
- Treatment of diarrhea caused by infection sensitive to the drug;
- Treatment of chronic colitis and enterocolitis;
- Prevention of infections in abdominal operations;
- Treatment of intestinal dysbiosis.

How to use:
Tablets prescribed for adults and children older than 6 years. For children under 6 years recommended the use of suspension.
Take 2 tablets every 6 hours, regardless of the meal. 5-7 day course of therapy.
The suspension is necessary before use Shake well, until smooth. Nifuroxazide dosage for children depending on age: from 2 to 6 months. - 0.5 -1 tsp (110-220 mg) twice a day, from 6 months. to 6 - 1 tsp (220 mg) three times a day for children older than 6 years and adults 1ch.l. (220 mg) 4 times a day.

Side effects:
Usually the drug does not cause side effects, but in rare cases, dyspepsia and diarrhea, even short-term gain. Side effects may not require medical treatment or discontinuation of the drug.
In cases of allergic reactions (rash, shortness of breath), the medication should be discontinued.

Contraindications:
Hypersensitivity to the nitrofuran derivative or any subsidiary components of the drug nifuroxazide.

Pregnancy:
During pregnancy, the drug can be used only on strict conditions and under the supervision of a physician.

Interactions with other drugs:
The drug has a high adsorption properties, which should be considered when taken with other drugs.
Interaction with systemic medications is impossible due to the fact that the drug detected in the blood only in trace concentrations.

Overdose:
Cases of overdose are not known. If there was a significant excess of the therapeutic dose nifuroxazide need a gastric lavage.

Product:
Film-coated tablets 100 mg, 24 tablets per pack.

Storage:
Store in a dry place, protected from the action of sunlight at room temperature (17-25 degrees Celsius).

Synonyms:
Enterofuryl, Lekor.

Ingredients:
Active substance: 100 mg nifuroxazide.
Additional substances: silica Si, potato starch, gelatin, talc, Mg, hypromellose, polyethylene glycol, quinoline yellow dioxide Ti.

In addition:
If symptoms of septicemia, the drug is not prescribed as monotherapy. If there are signs of dehydration, along with antimicrobial therapy requires rehydration therapy sufficient.
During treatment nifuroxazide need to completely eliminate alcohol intake, because of the possibility of a hypersensitivity reaction with tachycardia, anxiety, skin redness, feeling of heat, indigestion, difficulty breathing.
Nifuroxazide not affect the speed of psychomotor reactions, its reception is not a contraindication to working with complex machinery or drive vehicles.
Because of the lack of systemic effects of the drug, the possibility of their falling into the breast milk is minimal, which means that it can be used in women during lactation.

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