Novinet (Novynette) tablets (3x21) #63

Novinet (Novynette) tablets (3x21) #63
Manufacturer: Hungary
Product Code: 513
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Novinet (Novynette) tablets (3x21) #63

63 tablets

Mode of action:
Novinet is an oral contraceptive. In its composition contains a synthetic estrogen ethinyl estradiol (EE) and the progestogen desogestrel. Desogestrel, like all synthetic progestogens have a high affinity for the progesterone receptors, located in the area of ​​the hypothalamic-gipofizirnoy. Consequently, it is able to induce low dose effect of negative feedback. The result is a dramatic reduction in blocking the release of gonadotropins and ovulation. The value of a daily dose of the estrogen component is 20 micrograms can be attributed to Novinet mikrodozirovannym contraceptives. Progestogen and estrogen dose remains unchanged in all tablets per administration cycle. These drugs are called monophasic.

The contraceptive effect of the drug, in addition to the suppression of ovulation, is also due to changes in the endometrium, preventing implantation, and thickening the cervical mucus.
In addition to the contraceptive action of the drug has a number of therapeutic effects, which include: the regulation of the menstrual cycle, reducing menstrual blood loss, reduction in the incidence of inflammation in the pelvic organs, reducing the risk of ectopic pregnancy, reducing the risk of ovarian tumors, endometrial and breast cancer.
Desogestrel is absorbed from the digestive tract quickly. Bioavailability - up to 82%. Metabolized in the liver to form both active and inactive metabolites. Excretion of metabolites from the body is to the feces and urine.

Ethinyl estradiol is absorbed from the digestive tract fully and quickly. Is subjected to a large extent first-pass conjugation. Conjugates of ethinyl estradiol and enter into the process of enterohepatic circulation. About 60% of ethinyl estradiol is excreted in the feces, 40% is excreted in the urine.

Indications for use:
The need for contraception.

How to use:
Oral administration of the drug is advisable to start the day of occurrence of menstruation (the first day of the cycle). Duration - 21 days. The daily dose Novinet - 1 tablet. The tablets should preferably be taken at certain hours. After the use of the contents of the package (21 tablets) is a seven-day break. During this period, there menstrualnopodobnoe bleeding due to the termination of the Novinet. At the end of the drug was discontinued for the scheme is resumed.
Be receiving the first pill is not the first, and the second to fifth day of the menstrual cycle. In such a case, you should use additional methods of contraception during the first seven days of use of the drug. Start receiving Novinet after five days of onset of menstruation is not appropriate.
After delivery, an agent is given after 21 days. In the event which took place during this period of initiation of sexual intercourse is delayed until menstruation.

Breastfeeding this contraceptive is not recommended because the ability to inhibit lactation.
After an abortion Novinet appointed the first day since medical intervention.
If the set time is missed pill and since the crossing was less than twelve hours, the forgotten pill should be taken and follow the same scheme.
If after crossing has been more than twelve hours, requires the use of additional methods of contraception. The next day, in this case take two tablets of the preparation, followed by the established pattern.

Side effects:
- Migraine, headache, depression;
- Thromboembolic disease;
- Vomiting, nausea, cholelithiasis, ulcerative colitis, cholestatic jaundice, Crohn's disease;
- Amenorrhea, intermenstrual bleeding, changes in vaginal mucus, galactorrhea, inflammatory processes;
- Chloasma, erythema nodosum, rash, erythema;
- Fluid retention, weight gain, impaired carbohydrate metabolism;
- Allergic reactions.

Serious side effects that require immediate discontinuation of the drug:
- Arterial hypertension;
- Thrombotic disease (TEVLA, myocardial infarction, etc.);
- Loss of hearing;
- Sydenham's chorea, an exacerbation of SLE, hemolytic-uremic syndrome.

- Pregnancy;
- Moderate or severe hypertension;
- Dyslipidemia;
- Diseases caused by arterial thrombosis (ischemic stroke, myocardial infarction);
- Diabetic angiopathy;
- Venous thromboembolism in both personal and family history;
- Jaundice (cholestatic or on admission GCS);
- Severe liver disease;
- Endometrial hyperplasia;
- The existence or likelihood of estrogen-dependent tumors;
- Cholelithiasis;
- The risk of thromboembolism in both arterial and venous channel in;
- Migraine with symptoms of focal symptoms;
- Pancreatitis;
- Rotor syndrome, Gilbert, Dubin-Johnson;
- Severe itching;
- Tumors of the liver;
- Otosclerosis;
- Vaginal bleeding, the cause of which has not been established;
- Hypersensitivity;
- Smoking (women over 35 years of age).

Caution is required in epilepsy, atrial fibrillation, valvular disease, severe trauma, prolonged immobilization, varicose veins, the propensity to thrombosis, SLE, diabetes, Crohn's disease, ulcerative colitis.

Novinet contraindicated.

Interactions with other drugs:
Novinet reduce the effectiveness of barbiturates, carbamazepine, rifampicin, hydantoin, primidone, felbamate, topiramate, St. John's wort preparations.
Tetracycline and ampicillin, laxatives reduce the effectiveness of the drug.
In patients with diabetes increased need for glucose-lowering drugs.
Novinet reduces the effectiveness of caffeine, oral anticoagulants, theophylline, glucose-lowering drugs, tricyclic antidepressants, clofibrate, anxiolytics.

Metrorrhagia (mostly girls), vomiting, nausea, and headache. Symptomatic therapy. Gastric lavage is useful for two to three hours after ingestion.

Pills n / a, blisters, № 21 and 63.

Temperature 15 to 30 degrees Celsius.

Mersilon, Marvilon, regulon

One tablet ethinylestradiol 0.02 mg, 0.15 mg of desogestrel.
Other substances - magnesium stearate, quinoline, colloidal silicon, a-tocopherol, starch, povidone, lactose monohydrate, hypromellose, propylene glycol, stearic acid, Macrogol 6000.

In addition:
Before the appointment of the drug required medical examination.

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