Mildronat capsules 500mg #60

Mildronat capsules 500mg #60

Mildronat pharmachologic effect:

Cardioprotective, anti-hypoxic, anti-anginal, angioproteguoe action, is an analogue of gamma-butyrobetaine. It inhibits the synthesis of carnitine, resulting in increased production of gamma-butyrobetaine, which has vasodilatory properties. Under conditions of intense exercise balances the need for a balance between the tissues of oxygen and its delivery, prevents the accumulation in the cells and tissues of the decay products and toxins, protecting the cells from damage. Mildronat stimulates metabolic processes, increases efficiency (mental and physical), activates a humoral and cellular immunity. In ischemic tissues (myocardium, retina and brain) Mildronat redistributes blood flow to the affected areas. In acute ischemic myocardial injury slows the formation of necrosis reduces the rehabilitation period. With symptoms of heart failure Mildronat increases myocardial contractility, reduces the frequency and duration of angina attacks.

Mildronat indications for use:

Decreased efficiency; physical stress, including the athletes, in the treatment of coronary heart disease (angina, myocardial infarction, congestive heart failure and cardiomyopathy dyshormonal) withdrawal syndrome in chronic alcoholism (in combination with specific treatment of alcoholism); hemophthalmus and hemorrhage retina of various etiologies, thrombosis of central retinal vein and its branches, retinopathy of various etiologies (diabetic, hypertensive) in the treatment of acute and chronic circulatory disorders of the brain (stroke and chronic cerebrovascular insufficiency).

Mildronat used in the complex therapy:

- Chronic heart failure,
- Ischemic heart disease (myocardial infarction, angina pectoris)
- Dyshormonal cardiomyopathy,
- Chronic and acute disorders of cerebral circulation,
- As well as the withdrawal syndrome in patients with alcoholism;

Mildronat, other indications:

- Reduced performance,
- Postoperative period to reduce the rehabilitation period,
- Physical stress,
- Hemophthalmus,
- Thrombosis of the central retinal vein,
- Retinal hemorrhages of different etiologies, hypertensive and diabetic retinopathy (for parabulbarno administration)
- Chronic bronchitis and asthma (as an immunomodulator).

Application of Mildronat:

Mildronat used inside, intravenous, intramuscular and parabulbarno.

Athletes Mildronat administered before training at 0.5-1 g orally 2 times a day. During the preparation of the course of treatment - 2-3 weeks, during the period of competition - 10-14 days.
In the treatment of chronic alcoholism - inside of 0.5 g 4 times a day, by intravenous injection of 0.5 g twice a day. The duration of treatment of 7-10 days.
In the complex treatment of bronchial asthma Mildronat appoint 0.25 g daily for three weeks.

In diseases of the cardiovascular system:
In the treatment of stable angina - for 3-4 days on 250 mg three times a day, followed by 250 mg three times a day, 2 times a week for 1.5 months (in the complex treatment).
In the treatment of myocardial infarction and unstable angina - intravenously 0.5-1 g once a day, then into 250 mg twice a day for 3-4 days, then - twice weekly by 250 mg three times a day.

When cerebral circulatory disorders in the acute phase Mildronat naznachyut intravenously at 0.5 for 10 days g once a day, then take the drug orally at a daily dosage of 0.5-1 g
When degenerative and vascular diseases of the retina Mildronat parabulbarno prescribe 50 mg per day for 10 days.
When physical and mental stress - the inside of 0,25 g 3-4 times a day or intravenously at 500 mg once a day. Treatment duration of 10-14 days. The course is repeated if necessary.

Mildronat side effects:

It is rarely possible dyspepsia, increased heart rate, decreased or increased blood pressure, allergic reactions.

Mildronat contraindications:

Mildronat contraindicated in the presence of hypersensitivity to the drug, pregnancy and lactation, when intracranial hypertension, including intracranial tumors, disturbances of venous outflow.

Mildronat during pregnancy:

There is insufficient evidence of safety of Mildronate during pregnancy. To avoid adverse effects on the fetus Mildronate, it should not be used during pregnancy.

Interaction of Mildronat with other drugs:

Mildronat enhances the action of cardiac glycosides, vasodilatig funds and some antihypertensive drugs. Compatible with antiarrhythmic, antianginal drugs, antiplatelet, anticoagulant, bronchodilators and diuretics.
Care must be taken in combination with nifedipine, nitroglycerin, alpha-blockers (possible development of hypotension and moderate tachycardia).

Mildronat overdose:

There are no clinical data on drug overdose.

Mildronat product form:

1 capsule contains 500 mg mildronat 10 pieces in blister, 6 blisters per pack
1 ml solution for injection contains 100 mg mildronat 5 mL vial, 5 pieces in blister, 2 blisters in a carton box.

Mildronat storage conditions:

Refers to the list B. Store should be at a temperature no higher than 25 degrees Celsius, in a dry place.

Mildronat synonyms:

Mildroksin, MetaMax.

Mildronat composition:

Injection: colorless, transparent
active substance - Mildronat (3- (2,2,2 trimethylhydrasine) propionate dihydrate).
Excipients: Water for Injection.

Capsules:
Gelatin hard, white content - white crystalline powder, hygroscopic.
The active ingredient - meldonium (trimethylhydrasine propionate).
Other ingredients: calcium stearate, silica, potato starch.
Cover structure: gelatin, titanium dioxide (E171)

Mildronat pharmacological group:

• Medicines affecting mainly on tissue metabolism processes
• Drugs other chemical groups

Additionally:

In patients with chronic kidney disease and liver Mildronat for a long time used with caution. In acute coronary syndrome Mildronat does not apply to first-line drugs.
It is not enough data on the flow of Mildronate into breast milk. For the period of use Mildronate breast-feeding should be discontinued.

Write a review