Nystatin tabletspharmachologic effect:
Nystatin pathogenic fungi (parasitic fungi which cause disease in humans), and particularly in yeast fungi of the genus Candida, Aspergillus and on; For bacteria inactive. The drug is poorly absorbed; the bulk, ingested, is excreted in the feces.
Indications:
Nystatin applied for the prevention and treatment of diseases caused by yeast fungi of the genus Candida (Candidaalbicansi etc.). candidiasis (a fungal disease caused by yeasts), mucosal (oral, vaginal, and others.), the skin and internal organs (gastrointestinal tract, lungs, kidneys, etc..). For prophylaxis is indicated for the prevention of candidiasis in long-term treatment of penicillin and other antibiotics, especially when oral (by mouth) antibiotics tetracycline, chloramphenicol, neomycin, etc., As well as the weakened and depleted patients.
Nystatin mode of application:
Nystatin appointed interior tablets. Adults are 500,000 units 3-4 times per day or 250,000 ED 6 - 8 times a day. Daily dose - 1500000 - 3000000 units. In severe generalized candidiasis daily dose can be increased to 4000000 - 6000000 units. Children under the age of 1 year appoint 100,000 - 125,000 units, from 1 to 3 years -by 250,000 IU 3-4 times a day; older than 3 years - from 1,000,000 to 1,500,000 units per day in 4 divided doses.
The average duration of treatment - 10 - 14 days. Tablets are swallowed without chewing.
If it affects the mucous membranes of the mouth, pharynx and esophagus tablet (500,000 units 3-4 times daily after meals) was placed in the cheek, not liquid, to complete resorption.
In chronic recurrent and generalized candidiasis (repeated or continuous supply of the blood type of the fungus Candida) to repeat courses of treatment with breaks between courses of 2-3 weeks.
In the treatment of fungal infections of the skin and mucous membranes may be used nistatinovaya ointment. Application of ointments can be combined with nystatin inside.
When candidiasis lower intestine, as obesity (inflammation of the vagina) and vulvovaginitis (inflammation of the vulva and vagina) can be administered rectally (for insertion into the rectum) candles and vaginal globules (dosage form for administration into the vagina), containing 250000 and 500,000 units. They are administered 2 times a day, respectively, into the rectum or vagina; the average duration of the course - 10-14 days.
Nystatin side effects:
Nystatin low toxicity; side effects usually does not cause, in case of hypersensitivity to the antibiotic possible nausea, vomiting, diarrhea, fever, chills, and others. In such cases, reduce the dose.
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